Hypothermia and coagulation
نویسندگان
چکیده
منابع مشابه
Alterations in Coagulation Induced by Hypothermia and Acidosis in Swine1
Although clinical coagulopathy is associated with acidosis and hypothermia, the underlying mechanisms by which these factors alter the coagulation process remains unclear. The primary purpose of this study was to investigate the contributory effects of acidosis and hypothermia to the development of coagulopathy. Twentyfour pigs were randomly divided into control (pH 7.4, 39°C), acidotic (pH 7.1...
متن کاملEffects of In vitro hemodilution, hypothermia and rFVIIa addition on coagulation in human blood.
INTRODUCTION Coagulopathy can occur after hemorrhage, trauma and resuscitation, and has been associated with dilution of coagulation factors and hypothermia. Recombinant activated Factor VII (rFVIIa) has been used, often as a last resort, to improve hemostasis in trauma/hemorrhage patients with coagulopathy. The aim of this study was to further characterize the effects of rFVIIa on various coag...
متن کاملThe effects of hypothermia on fibrinogen metabolism and coagulation function in swine.
Clinical coagulopathy frequently occurs in the presence of hypothermia. The primary purpose of this study was to investigate the effects of hypothermia on clotting protein fibrinogen metabolism and on coagulation function in a swine model. Twelve pigs were randomly allocated into control and hypothermia groups. Hypothermia of 32 degrees C was induced using a blanket with circulating water at 4 ...
متن کاملProceedings: Cryofibrinogenaemia and activation of the coagulation/lysis systems in accidental hypothermia of the elderly.
pathologists have experience of unexpectedly low carboxyhaemoglobin saturation levels in fatal carbon-monoxide poisoning. The textbooks give 60% as the minimum lethal concentration for healthy subjects. Why then should apparently fit persons, below the age of 70, die with saturation levels below 50% ? A series of 300 included 24 such cases, with values from 40 to 490o (palladium chloride analys...
متن کاملA thromboelastometric evaluation of the effects of hypothermia on the coagulation system.
BACKGROUND Hypothermia may be accidental or therapeutic. Therapeutic hypothermia is increasingly used as treatment for various conditions, e.g., neuroprotection after cardiac arrest. Hypothermia leads to an impairment of the coagulation system, but the degree of impairment has been difficult to determine. Most studies have been performed on plasma instead of whole blood. We therefore evaluated ...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2012
ISSN: 1364-8535
DOI: 10.1186/cc11278